Prenatal diagnosis of isolated fetal gallbladder duplicationassociated with chromosomal mutation (46,X,t(X;10(p11.2;Q24.3)

GÜVENDAĞ GÜVEN E. S., GÜVEN S., KART C., CÖMERT E. H.

PRENATAL DIAGNOSIS, vol.36, pp.77, 2016 (SCI-Expanded)

  • Publication Type: Article / Abstract
  • Volume: 36
  • Publication Date: 2016
  • Journal Name: PRENATAL DIAGNOSIS
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.77
  • Karadeniz Technical University Affiliated: Yes

Abstract

OBJECTIVES

: Gallbladder duplication is a rare congenital

malformation, occurring in about one per 4000 births resulting

in two separate gallbladder cavities, each with a cystic duct.

Here, we describe a chromosomal mutation (46,X,t(X;10

(p11.2;Q24.3) with duplicated fetal gallbladder which it was

not described previously.

METHODS

: A 22-year-old woman

(gravida 1, parite 0) was referred to our hospital at 18 weeks

of gestation for a routine ultrasound examination. A fetal

duplication of gallbladder was diagnosed with ultrasonography

and fetal magnetic resonance imaging. Amniocentesis was

performed for prenatal diagnosis, and it was revealed that 46,

X,t(X;10(p11.2;Q24.3). At 39 weeks of gestation, a 2480g male

baby was delivered by cesarean section.

RESULTS

: Isolated

duplication of gallbladder was observed after birth. The baby

has been born healthy otherwise.

CONCLUSIONS

: The

karyotype

‘

46,X,t(X;10(p11.2;Q24.3)

’

may be associated with

isolated duplication of gallbladder.