Acute liver failure associated with metabolic diseases: A 10-year single-center experience


GÜVEN B., Sag E., KARAGÜZEL G., ÇAKIR M.

PEDIATRICS INTERNATIONAL, vol.62, no.5, pp.609-614, 2020 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 62 Issue: 5
  • Publication Date: 2020
  • Doi Number: 10.1111/ped.14230
  • Journal Name: PEDIATRICS INTERNATIONAL
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, Agricultural & Environmental Science Database, BIOSIS, CAB Abstracts, CINAHL, EMBASE, MEDLINE, Veterinary Science Database
  • Page Numbers: pp.609-614
  • Keywords: acute liver failure, metabolic disease, pediatric, CHILDREN, DISORDERS, TRANSPLANTATION, DEFICIENCY, OUTCOMES, INFANTS
  • Karadeniz Technical University Affiliated: Yes

Abstract

Background Acute liver failure (ALF) is a rare multisystemic disease occurring in individuals with no history of liver disease, characterized by coagulopathy and / or hepatic encephalopathy secondary to acute liver injury. It is mostly caused by viral infections, drug intoxication, and metabolic diseases (MD), and can also have an indeterminate etiology. In this study, we aimed to evaluate the demographic and clinical characteristics and clinical outcomes of the patients that presented to our clinic with MD-associated ALF.