Comparison of the serum cytokine levels before and after adrenocorticotropic hormone (ACTH) therapy in patients with infantile spasm

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Türe E., KAMAŞAK T., CORA M., ŞAHİN S., ARSLAN E. A., KAKLIKAYA N., ...More

SEIZURE-EUROPEAN JOURNAL OF EPILEPSY, vol.41, pp.112-115, 2016 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 41
  • Publication Date: 2016
  • Doi Number: 10.1016/j.seizure.2016.06.021
  • Journal Name: SEIZURE-EUROPEAN JOURNAL OF EPILEPSY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.112-115
  • Keywords: Infantile spasm, Cytokines, IL-1beta, IL-6, IL-17A, IL-2, WEST-SYNDROME, EPILEPSY, INTERLEUKIN-6, PATHOGENESIS
  • Karadeniz Technical University Affiliated: Yes

Abstract

Purpose: Infantile spasm is an age-dependent epileptic syndrome seen in infancy or early childhood. Although studies have investigated the epilepsy-cytokine relationship, there has been insufficient research into the relation between cytokines and infantile spasm. The purpose of this study was to examine the role of cytokines in the pathogenesis of infantile spasm by investigating cytokine levels before and 1 month after adrenocorticotropic hormone (ACTH) therapy in patients diagnosed with the condition.