Essential oil composition and antimicrobial activity of Inula thapsoides subsp. thapsoides from Turkey

Üçüncü O., Gaydan F., Guelec C., Çoşkunçelebi K., Yaylı N.

Asian Journal of Chemistry, vol.20, no.2, pp.1049-1054, 2008 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 20 Issue: 2
  • Publication Date: 2008
  • Journal Name: Asian Journal of Chemistry
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.1049-1054
  • Keywords: Antimicrobial activity, Asteraceae, Essential oil, GC-MS, Inula thapsoides subsp. thapsoides
  • Karadeniz Technical University Affiliated: Yes


The composition of the essential oil isolated from the air-dried Inula thapsoides subsp. thapsoides was analyzed by GC-MS. 51 Components were identified in the essential oil and the main components of this species were dihydro edulan (12.4 %), β-selinene (9.9 %), caryophyllene oxide (9.0 %), pentacosane (8.3 %) and epi-α-cadinol (5.2 %). The isolated essential oil of I. thapsoides subsp. thapsoides was also tested for antimicrobial activity against the bacteria E. coli, Y. pseudotuberculosis, K. pneumoniae, S. marcescens, E. faecalis, S. aureus, B. subtilis and the fungus C. albicans and C. tropicalis at maximum essential oil concentration in acetone of 1000 μg/mL and they showed moderate antibacterial activity against Gram-positive and Gram-negative bacteria.