A new player in chronic kidney disease mineral and bone disorder: tenascin-C

OZKAN G., ULUSOY Ş., GÜVERCİN B., MENTEŞE A., KARAHAN S. C., YAVUZ A.

INTERNATIONAL JOURNAL OF ARTIFICIAL ORGANS, cilt.38, sa.9, ss.481-487, 2015 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 38 Sayı: 9
  • Basım Tarihi: 2015
  • Doi Numarası: 10.5301/ijao.5000436
  • Dergi Adı: INTERNATIONAL JOURNAL OF ARTIFICIAL ORGANS
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.481-487
  • Karadeniz Teknik Üniversitesi Adresli: Evet

Özet

Aims: Chronic kidney disease-mineral and bone disorder (CKD-MBD) is a condition frequently observed in CKD. The search for a reliable and easy to use biomarker in the diagnosis of CKD-MBD is continuing. Tenascin-C (TN-C) is an important extracellular (ECM) protein synthesized by osteoblasts during bone growth and morphogenesis. The purpose of this study was to assess the relation between inflammation and MBD and TN-C in HD patients and to identify a new marker that can be used to help diagnose CKD-MBD.