The effect of ethyl pyruvate and N-acetylcysteine on ischemia-reperfusion injury in an experimental model of ischemic stroke

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Turkmen S., Gonenc O. C., Karaca Y., Menteşe A., Demir S., Beyhun E., ...Daha Fazla

AMERICAN JOURNAL OF EMERGENCY MEDICINE, cilt.34, sa.9, ss.1804-1807, 2016 (SCI-Expanded, Scopus)

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 34 Sayı: 9
  • Basım Tarihi: 2016
  • Doi Numarası: 10.1016/j.ajem.2016.06.003
  • Dergi Adı: AMERICAN JOURNAL OF EMERGENCY MEDICINE
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.1804-1807
  • Karadeniz Teknik Üniversitesi Adresli: Evet

Özet

Introduction: Reperfusion therapies play an important role in early-period treatment for patients presenting to the emergency department due to stroke. However, the ischemia-reperfusion injury that may occur with reperfusion must then be considered. The purpose of this study was to determine the effectiveness of N-acetylcysteine (NAC) and ethyl pyruvate in preventing ischemia-reperfusion injury.