The effect of ethyl pyruvate and N-acetylcysteine on ischemia-reperfusion injury in an experimental model of ischemic stroke

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Turkmen S., Gonenc O. C., Karaca Y., Menteşe A., Demir S., Beyhun E., ...More

AMERICAN JOURNAL OF EMERGENCY MEDICINE, vol.34, no.9, pp.1804-1807, 2016 (SCI-Expanded) identifier identifier identifier


Introduction: Reperfusion therapies play an important role in early-period treatment for patients presenting to the emergency department due to stroke. However, the ischemia-reperfusion injury that may occur with reperfusion must then be considered. The purpose of this study was to determine the effectiveness of N-acetylcysteine (NAC) and ethyl pyruvate in preventing ischemia-reperfusion injury.