Copy For Citation
KURAL B. V., DEĞER O., Erem C., YUCESAN F., Barlak Y., Turan I., ...More
TURKISH JOURNAL OF BIOCHEMISTRY-TURK BIYOKIMYA DERGISI, vol.38, no.3, pp.280-285, 2013 (SCI-Expanded)
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Publication Type:
Article / Article
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Volume:
38
Issue:
3
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Publication Date:
2013
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Doi Number:
10.5505/tjb.2013.41033
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Journal Name:
TURKISH JOURNAL OF BIOCHEMISTRY-TURK BIYOKIMYA DERGISI
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Journal Indexes:
Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
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Page Numbers:
pp.280-285
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Keywords:
metabolic syndrome, LPIN1, lipin-1, INSULIN-RESISTANCE, LIPIN, ASSOCIATION, POLYMORPHISMS, BIOSYNTHESIS, OBESITY, FAMILY, ROLES
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Karadeniz Technical University Affiliated:
Yes
Abstract
Objective: Metabolic syndrome (MetS) is a complex disease characterized by insulin resistance, abdominal obesity, hyperglycemia, hypertension, hypertriglyceridemia and low HDL-cholesterol level. The aim of the study was to evaluate the sequence variations in the LPIN1 gene in MetS. This gene codes lipin-1 protein which functions as Mg-dependent phosphatidic phosphatase enzyme and transcriptional coactivator.