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Altinkaynak Y., KURAL B., Akcan B. A., Bodur A., ÖZER YAMAN S., YULUĞ E., ...More
BIOMEDICINE & PHARMACOTHERAPY, vol.108, pp.1524-1534, 2018 (SCI-Expanded)
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Publication Type:
Article / Article
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Volume:
108
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Publication Date:
2018
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Doi Number:
10.1016/j.biopha.2018.09.171
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Journal Name:
BIOMEDICINE & PHARMACOTHERAPY
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Journal Indexes:
Science Citation Index Expanded (SCI-EXPANDED), Scopus
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Page Numbers:
pp.1524-1534
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Keywords:
Antioxidant, Apoptosis, Glutathione, Inflammation, L-Theanine, CISPLATIN-INDUCED NEPHROTOXICITY, GAMMA-GLUTAMYL-TRANSPEPTIDASE, ACUTE KIDNEY INJURY, UNIQUE AMINO-ACID, OXIDATIVE STRESS, INDUCED NEUROTOXICITY, UP-REGULATION, LIVER-INJURY, GLUTATHIONE, METABOLISM
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Karadeniz Technical University Affiliated:
Yes
Abstract
Background/aim: L-theanine is the unique amino acid found in tea plants, has antioxidant and antiinflammatory activities, and functions in mental concentration and sleep quality. In this study, it is aimed to investigate the effects of L-theanine on doxorubicin (DOX, a chemotherapeutic agent) induced nephrotoxicity in rats, especially via GSH related enzymes.