Reduced cerebrospinal fluid levels of interleukin-10 in children with febrile seizures

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ŞAHİN S., Uysal S., Yentur S. P., Kacar A.

SEIZURE-EUROPEAN JOURNAL OF EPILEPSY, cilt.65, ss.94-97, 2019 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 65
  • Basım Tarihi: 2019
  • Doi Numarası: 10.1016/j.seizure.2019.01.008
  • Dergi Adı: SEIZURE-EUROPEAN JOURNAL OF EPILEPSY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.94-97
  • Karadeniz Teknik Üniversitesi Adresli: Evet

Özet

Purpose: The exact etiology of febrile seizures (FS) is still unclear. However, it is thought that cytokine network activation may have a causative role. Therefore, this study aimed to evaluate the levels of interleukin-12 (IL-12) as a proinflammatory cytokine, interleukin-10 (IL-10) as an anti-inflammatory cytokine, and interferon-beta (IFN-beta), a marker of toll-like receptor-3 activation as a host response to viruses. These cytokine levels were analyzed in the cerebrospinal fluid (CSF) of children after a FS.