TGF-beta and TNF-alpha producing effects of losartan and amlodipine on human mononuclear cell culture

KAYNAR K., Ulusoy S., OVALI E., VANIZOR B., DIKMEN T., GUL S.

NEPHROLOGY, vol.10, no.5, pp.478-482, 2005 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 10 Issue: 5
  • Publication Date: 2005
  • Doi Number: 10.1111/j.1440-1797.2005.00462.x
  • Journal Name: NEPHROLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.478-482
  • Keywords: amlodipine, losartan, TGF-beta, TNF-alpha, mononuclear cell culture, TUMOR-NECROSIS-FACTOR, ISCHEMIC-HEART-DISEASE, GROWTH-FACTOR-BETA, ANGIOTENSIN-II, INSULIN SENSITIVITY, HYPERTENSION, EXPRESSION, ATHEROSCLEROSIS, CYTOKINES, TRIAL
  • Karadeniz Technical University Affiliated: Yes

Abstract

Aim: The modulation of cytokine release, which affects adhesion of leucocytes to endothelial cells, and proliferation of peripheral blood mononuclear cells with antihypertensive drugs was explored.