Simple and Fast Determination of Terbinafine in Human Urine by Dilute and Shoot HPLC-DAD Using a Core-Shell Column

YILDIRIM S., Demirdas G., Fidan M., YAŞAR A.

COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING, cilt.24, sa.3, ss.342-351, 2021 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 24 Sayı: 3
  • Basım Tarihi: 2021
  • Doi Numarası: 10.2174/1386207323666200709171504
  • Dergi Adı: COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, BIOSIS, Biotechnology Research Abstracts, CAB Abstracts, Chemical Abstracts Core, EMBASE, MEDLINE, Veterinary Science Database
  • Sayfa Sayıları: ss.342-351
  • Anahtar Kelimeler: Core-shell columns, dilute and shoot approach, fast analysis, high-performance liquid chromatography, terbinafinue rine, PERFORMANCE LIQUID-CHROMATOGRAPHY, LC-MS/MS ASSAY, HUMAN PLASMA, QUANTITATIVE-ANALYSIS, MASS-SPECTROMETRY, QUANTIFICATION, EXTRACTION, SPIRONOLACTONE, METABOLITES, VALIDATION
  • Karadeniz Teknik Üniversitesi Adresli: Evet

Özet

Background: Terbinafine is an allylamine antifungal that is effective against many fungi, dermatophytes and moulds. Analytical methods are required for the determination of terbinafine in biological fluids to perform therapeutic drug monitoring and pharmacokinetic studies.