Adverse skin reactions caused by L-asparaginase: Allergy or infection?

BAHADIR A., Abul M. H., Reis P. G., ERDURAN E., ORHAN F.

ASTIM ALLERJI IMMUNOLOJI, vol.13, no.3, pp.130-133, 2015 (ESCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 13 Issue: 3
  • Publication Date: 2015
  • Doi Number: 10.5578/aai.10890
  • Journal Indexes: Emerging Sources Citation Index (ESCI), Scopus, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.130-133
  • Karadeniz Technical University Affiliated: Yes


Objective: L-asparaginase (L-ASP) is one of the indispensible medications used in the treatment of acute lymphoblastic leukemia (ALL); however, the allergic reactions caused by the drug limit its use. 52 patients (37 were low risk, 15 were high risk) who were followed for ALL between January 2010 and July 2014 and who developed local and systemic reactions associated with Escherichia coli L-ASP were evaluated.