Novel piperazine-substituted silicon phthalocyanines exert anti-cancer effects against breast cancer cells


NALÇAOĞLU A. , SARI C. , DEĞİRMENCİOĞLU İ. , CELEP EYÜPOĞLU F.

PHOTODIAGNOSIS AND PHOTODYNAMIC THERAPY, vol.37, 2022 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 37
  • Publication Date: 2022
  • Doi Number: 10.1016/j.pdpdt.2022.102734
  • Title of Journal : PHOTODIAGNOSIS AND PHOTODYNAMIC THERAPY
  • Keywords: Breast neoplasms, Photodynamic therapy, Silicon phthalocyanine, Piperazine, Reactive oxygen species, PHOTODYNAMIC THERAPY, IN-VITRO, ANTIPROLIFERATIVE ACTIVITY, MECHANISMS, TUMOR, APOPTOSIS, PHARMACOKINETICS, DERIVATIVES, ACTIVATION, INDUCTION

Abstract

Background: Photodynamic therapy (PDT) is one of the effective methods that can be used in cancer treatment. In this study, we aimed to investigate the PDT-mediated anti-cancer effects of newly synthesized piperazinesubstituted silicon phthalocyanine molecules on breast cancer cells.