Serum carbonic anhydrase autoantibodies in metabolic syndrome

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Copy For Citation

ALVER A., MENTEŞE A., Erem C., DEĞER O., Koçak M., Keha E. E.

Diabetes and Metabolic Syndrome: Clinical Research and Reviews, vol.3, no.4, pp.211-213, 2009 (SCI-Expanded)

• Publication Type: Article / Article
• Volume: 3 Issue: 4
• Publication Date: 2009
• Doi Number: 10.1016/j.dsx.2009.07.011
• Journal Name: Diabetes and Metabolic Syndrome: Clinical Research and Reviews
• Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
• Page Numbers: pp.211-213
• Karadeniz Technical University Affiliated: Yes

Abstract

Aims

Carbonic anhydrase (CA) autoantibodies have been observed in various autoimmune and idiopathic diseases right now. The aim of this study was to investigate the presence of anti-carbonic anhydrase I and II antibodies in subjects with metabolic syndrome (MetS).

Methods

43 subjects with MetS and 30 non-MetS subjects (controls) were included in the study. Carbonic anhydrase autoantibodies were screened by ELISA.

Results

Anti-CA I antibody was detected in 7 of 43 subjects with MetS. The antibody-positive prevalence of MetS group (16%) was found to be significantly higher compared with that of control group (p < 0.05). There were no significant changes in positive rate of anti-CA II antibody. Positive results were obtained in 2 of 43 subjects with MetS.

Conclusions