An Ossifying Fıbroma Exhibiting Unusual Expansion Pattern And Periosteal Reaction: Case Report


Bakal A., İlkul S. İ.

2. INTERNATIONAL WARSAW SCIENTIFIC RESEARCH AND INNOVATION CONGRESS, Warszawa, Polonya, 25 - 26 Ocak 2026, ss.648-655, (Tam Metin Bildiri)

  • Yayın Türü: Bildiri / Tam Metin Bildiri
  • Basıldığı Şehir: Warszawa
  • Basıldığı Ülke: Polonya
  • Sayfa Sayıları: ss.648-655
  • Karadeniz Teknik Üniversitesi Adresli: Evet

Özet

Introduction and Purpose: Ossifying fibroma is a benign fibro-osseous lesion characterized by the replacement of normal bone with fibrous tissue containing variable amounts of mineralized material. It is typically well circumscribed, encapsulated, and slow growing, and most commonly occurs in the posterior mandible. The lesion is usually asymptomatic and may present with findings such as bony expansion and displacement of adjacent teeth. A definitive diagnosis is established through combined clinical, radiological, and histopathological evaluation. However, atypical radiographic features, particularly in pediatric patients, may complicate the differential diagnosis. The purpose of this case report is to present an atypical mandibular ossifying fibroma exhibiting dominant buccal expansion and periosteal reaction, to highlight diagnostic challenges, and to emphasize the importance of correlating clinical, radiographic, and histopathological findings in the evaluation of mixed radiolucent–radiopaque lesions. Case Presentation: A nine-year-old female patient presented with a painless swelling in the left posterior mandible that had gradually increased in size. Clinical examination revealed a firm intraoral swelling without neurosensory deficit. Panoramic radiography demonstrated a mixed radiolucent–radiopaque lesion extending superiorly from the crown of the unerupted second premolar. Cone-beam computed tomography revealed a lesion measuring 17.5 × 14.3 × 17.3 mm, partially encapsulated, showing prominent buccal cortical expansion and internal calcifications. Atypically, a periosteal reaction was observed in the adjacent cortical bone. The differential diagnosis included ossifying fibroma, fibrous dysplasia, calcifying odontogenic cysts, and adenomatoid odontogenic tumor. The lesion was surgically excised, and histopathological examination confirmed the diagnosis of ossifying fibroma. No recurrence was observed during a three-year follow-up period. Keywords: ossifying fibroma, mandible, benign tumor, expansion