Protective Effects of Ursolic Acid in the Kidneys o Diabetic Rats

Bacanli M., Aydin S., Anlar H. G., Cal T., Bucurgat U. U., Ari N., ...Daha Fazla

TURKISH JOURNAL OF PHARMACEUTICAL SCIENCES, cilt.15, sa.2, ss.166-170, 2018 (ESCI) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 15 Sayı: 2
  • Basım Tarihi: 2018
  • Doi Numarası: 10.4274/tjps.49469
  • Dergi Adı: TURKISH JOURNAL OF PHARMACEUTICAL SCIENCES
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.166-170
  • Karadeniz Teknik Üniversitesi Adresli: Evet

Özet

Objectives: Diabetes, a heteregenous metabolic and chronic disease, is a growing health problem in most countries. It has been claimed that diabetes is associated with the increased formation of free radicals and decreased in antioxidant potential. Oxidative stress formed in diabetes may cause DNA damage in the tissues. Ursolic acid, a well-known pentacylic triterpene, is commonly used in traditional Chinese medicine due to its beneficial health effects such as antioxidant, anticancer, and antiulcer properties. The aim of this study was to investigate the effects of ursolic acid in the kidneys of Wistar albino rats with streptozotocin-induced diabetes.