Protective Effects of Ursolic Acid in the Kidneys o Diabetic Rats


Bacanli M., Aydin S., Anlar H. G. , Cal T., Bucurgat U. U. , Ari N., ...More

TURKISH JOURNAL OF PHARMACEUTICAL SCIENCES, vol.15, no.2, pp.166-170, 2018 (Journal Indexed in ESCI) identifier identifier

  • Publication Type: Article / Article
  • Volume: 15 Issue: 2
  • Publication Date: 2018
  • Doi Number: 10.4274/tjps.49469
  • Title of Journal : TURKISH JOURNAL OF PHARMACEUTICAL SCIENCES
  • Page Numbers: pp.166-170

Abstract

Objectives: Diabetes, a heteregenous metabolic and chronic disease, is a growing health problem in most countries. It has been claimed that diabetes is associated with the increased formation of free radicals and decreased in antioxidant potential. Oxidative stress formed in diabetes may cause DNA damage in the tissues. Ursolic acid, a well-known pentacylic triterpene, is commonly used in traditional Chinese medicine due to its beneficial health effects such as antioxidant, anticancer, and antiulcer properties. The aim of this study was to investigate the effects of ursolic acid in the kidneys of Wistar albino rats with streptozotocin-induced diabetes.