Carbon dioxide pneumoperitoneum induces systemic oxidative stress: a clinical study

ARAN T., Unsal M. A., GÜVEN S., KART C., Cetin E. C., ALVER A.

EUROPEAN JOURNAL OF OBSTETRICS & GYNECOLOGY AND REPRODUCTIVE BIOLOGY, vol.161, no.1, pp.80-83, 2012 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 161 Issue: 1
  • Publication Date: 2012
  • Doi Number: 10.1016/j.ejogrb.2011.11.027
  • Journal Name: EUROPEAN JOURNAL OF OBSTETRICS & GYNECOLOGY AND REPRODUCTIVE BIOLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.80-83
  • Keywords: Biochemical marker, Ischemia-modified albumin, Laparoscopy, Safety, INCREASED INTRAABDOMINAL PRESSURE, ALBUMIN COBALT BINDING, MYOCARDIAL-ISCHEMIA, LAPAROSCOPIC CHOLECYSTECTOMY, BLOOD-FLOW, ANTIOXIDANT, SURGERY, MORPHOLOGY, ASSAY, CONTRACTILITY
  • Karadeniz Technical University Affiliated: Yes

Abstract

Objective: To investigate the effect of carbon dioxide pneumoperitoneum on systemic oxidative stress by using serum oxidative stress markers (ischemia modified albumin (IMA), malondialdehyde (MDA), total oxidant status (TOS), total antioxidant status (TAS) and oxidative stress index (OSI)) and to compare their effectiveness at clinically accepted safe intra-abdominal pressure levels (<12 mmHg).