Synthesis of novel Schiff bases and azol-beta-lactam derivatives starting from morpholine and thiomorpholine and investigation of their antitubercular, antiurease activity, acethylcolinesterase inhibition effect and antioxidant capacity

CEBECI, Yildiz; BAYRAK, HACER; ŞIRIN, Yakup

doi:10.1016/j.bioorg.2019.102928

Synthesis of novel Schiff bases and azol-beta-lactam derivatives starting from morpholine and thiomorpholine and investigation of their antitubercular, antiurease activity, acethylcolinesterase inhibition effect and antioxidant capacity

Atıf İçin Kopyala

CEBECI Y. U., BAYRAK H., ŞIRIN Y.

BIOORGANIC CHEMISTRY, cilt.88, 2019 (SCI-Expanded)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 88
Basım Tarihi: 2019
Doi Numarası: 10.1016/j.bioorg.2019.102928
Dergi Adı: BIOORGANIC CHEMISTRY
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Anahtar Kelimeler: Schiff base, beta-Lactam, Morpholine, Thiomorpholine, Azole, Antitubercular activity, Antiurease activity, Acethylcolinesterase, Antioxidant, BIOLOGICAL EVALUATION, ANTIBACTERIAL, PRODUCTS, DRUG
Karadeniz Teknik Üniversitesi Adresli: Evet

Özet

In this study, new Schiff bases and beta-lactam derivatives containing morpholine and thio morpholine nuclei were synthesized. Antimicrobial, antioxidant, antimicrobial and antioxidant properties of all synthesized compounds were investigated and highly effective products were obtained. In this context, new effective structures were introduced to the literature.