Anesthetic management in a patient with Marsili syndrome: A Case Report
ANNALS OF CLINICAL AND ANALYTICAL MEDICINE, cilt.17, sa.8, ss.864-867, 2026 (ESCI)
- Yayın Türü: Makale / Vaka Takdimi
- Cilt numarası: 17 Sayı: 8
- Basım Tarihi: 2026
- Doi Numarası: 10.4328/acam.22747
- Dergi Adı: ANNALS OF CLINICAL AND ANALYTICAL MEDICINE
- Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI)
- Sayfa Sayıları: ss.864-867
- Karadeniz Teknik Üniversitesi Adresli: Evet
Özet
Abstract
IntroductionMarsili syndrome is a rare congenital disorder characterized by markedly reduced pain perception with preserved tactile and proprioceptive functions. Altered nociception presents unique challenges for anesthetic management, particularly regarding analgesic dosing and intraoperative monitoring.Case PresentationA 17-year-old male with Marsili syndrome underwent surgical debridement of an infected leg prosthesis. Preoperative assessment revealed diminished pain and temperature sensation, lip atrophy, and a potentially difficult airway. General anesthesia was induced and maintained with propofol and remifentanil, guided by bispectral index (BIS) monitoring. The intraoperative course was uneventful, with stable hemodynamic parameters, and no postoperative analgesia was required.ConclusionThis case demonstrates that safe anesthetic management in patients with Marsili syndrome can be achieved through individualized, carefully titrated anesthetic techniques and vigilant monitoring. Further clinical experience is required to establish standardized anesthetic guidelines for this rare condition.