Akademik Veri Yönetim Sistemi
Cocuk Enfeksiyon Dergisi, cilt.17, sa.1, ss.59-62, 2023 (ESCI)
Papiliotrema laurentii, previously known as Cryptococcus laurentii, has rarely been diagnosed as the etiological pathogen able to cause human infections. Clinical manifestations of P. laurentii ranges from skin lesions to fungemia. P. laurentii fungemia has been reported extremely rare, es-pecially in patients with risk factors such as chemotherapy, corticoster-oids, HIV infection, indwelling central venous catheter and prematurity. This study aimed to report a case of fungemia due to P. laurentii in an infant with Prader Willi syndrome. Despite fluconazole treatment, yeast was isolated three times from blood cultures taken one day apart. Flucona-zole was switched to liposomal amphotericin B (5 mg/kg) therapy and continued for two weeks after the first report of unyielded Papiliotrema laurentii. The patient’s clinical condition improved and was discharged home without any complication. To the best of our knowledge, this is the first case of P. laurentii fungemia in an immunocompetent infant.