Comparison of Quality Parameters of Safflower (Carthami flos) Samples Sold in the Market with Pharmacopoeia tests


Gökkaya İ., Şahinöz M. Z., İleri Özler H. K., Peraşan M. H., Altınbaş M. K., Renda G., ...Daha Fazla

IConPB2025, Denizli, Türkiye, 3 - 06 Eylül 2025, ss.178, (Özet Bildiri)

  • Yayın Türü: Bildiri / Özet Bildiri
  • Basıldığı Şehir: Denizli
  • Basıldığı Ülke: Türkiye
  • Sayfa Sayıları: ss.178
  • Karadeniz Teknik Üniversitesi Adresli: Evet

Özet

Carthamus tinctorius L. (Asteraceae) is used worldwide for the treatment of bronchitis, rheumatism, diabetes, depression, menstrual disorders, postpartum hemorrhage, mastalgia, scabies, skin disorders, and baldness; as an analgesic, antipyretic, wound healer, laxative, and antidote for poisoning (1,2). C. tinctorius is listed in many pharmacopoeias worldwide, including the Turkish Pharmacopoeia 2023 (3). This study aims to evaluate the quality parameters of ten C. tinctorius flower samples obtained from five different provinces with pharmacopoeial tests based on the Turkish Pharmacopoeia 2023. Morphological studies, microscopic analysis, and several physicochemical tests (absorbance, foreign matter, loss on drying, total ash, and insoluble ash in hydrochloric acid) of all samples were carried out as described in the pharmacopoeia. The samples showed the morphological characteristics and microscopic components specified in the pharmacopoeia. On the other hand, it was found that all samples included contaminants, including insects, hair remnants, stone fragments, and other plant organs. The absorbance values for yellow pigment ranged between 0.296 and 0.442, with only one sample meeting pharmacopoeial criteria. The absorbance readings for the red pigment ranged between 0.180 and 0.295, with none of the samples satisfying the pharmacopoeial standards. The total ash values of all samples were under 10%, and the insoluble ash values in hydrochloric acid were below 3%. The ash content tests of the samples complied with the limits specified in the pharmacopoeia. Taken collectively, commercially available C. tinctorius samples fail to satisfy pharmacopoeial criteria. The public obtains herbal products for therapeutic use from unregulated sources such as herbalists, the internet, and social media. Products supplied under these circumstances show significant quality issues, as demonstrated by our study's findings. We recommend that herbal products be cultivated under supervision, adhering to established good agricultural practices, and that they be sold only after preparation in accordance with GMP