The efficacy of octreotide in the therapy of acute radiation-induced diarrhea: A randomized controlled study


YAVUZ M., YAVUZ A., Aydin F. , Can G. , Kavgaci H.

INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, vol.54, no.1, pp.195-202, 2002 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 54 Issue: 1
  • Publication Date: 2002
  • Doi Number: 10.1016/s0360-3016(02)02870-5
  • Title of Journal : INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS
  • Page Numbers: pp.195-202

Abstract

Purpose: Although the somatostatin analog octreotide is currently used in the treatment of chemotherapy-induced diarrhea and secretory diarrhea associated with various disorders, its role in the management of radiation enteritis is not well defined. We performed a randomized study that compared octreotide acetate with diphenoxylate hydrochloride plus atropine sulfate, the drug commonly used as therapy for acute radiation-induced diarrhea (ARID).