The efficacy of octreotide in the therapy of acute radiation-induced diarrhea: A randomized controlled study
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, cilt.54, sa.1, ss.195-202, 2002 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 54 Sayı: 1
- Basım Tarihi: 2002
- Doi Numarası: 10.1016/s0360-3016(02)02870-5
- Dergi Adı: INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.195-202
- Anahtar Kelimeler: pelvic radiation therapy, radiation-induced diarrhea, octreotide, CHEMOTHERAPY-INDUCED DIARRHEA, ACTING SOMATOSTATIN ANALOG, BONE-MARROW TRANSPLANT, SMS 201-995, LOPERAMIDE, ACETATE, PATIENT, TRIAL, SMS-201-995, SANDOSTATIN
- Karadeniz Teknik Üniversitesi Adresli: Evet
Özet
Purpose: Although the somatostatin analog octreotide is currently used in the treatment of chemotherapy-induced diarrhea and secretory diarrhea associated with various disorders, its role in the management of radiation enteritis is not well defined. We performed a randomized study that compared octreotide acetate with diphenoxylate hydrochloride plus atropine sulfate, the drug commonly used as therapy for acute radiation-induced diarrhea (ARID).