The efficacy of octreotide in the therapy of acute radiation-induced diarrhea: A randomized controlled study

YAVUZ M., YAVUZ A., Aydin F., Can G., Kavgaci H.

INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, cilt.54, sa.1, ss.195-202, 2002 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 54 Sayı: 1
  • Basım Tarihi: 2002
  • Doi Numarası: 10.1016/s0360-3016(02)02870-5
  • Dergi Adı: INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.195-202
  • Anahtar Kelimeler: pelvic radiation therapy, radiation-induced diarrhea, octreotide, CHEMOTHERAPY-INDUCED DIARRHEA, ACTING SOMATOSTATIN ANALOG, BONE-MARROW TRANSPLANT, SMS 201-995, LOPERAMIDE, ACETATE, PATIENT, TRIAL, SMS-201-995, SANDOSTATIN
  • Karadeniz Teknik Üniversitesi Adresli: Evet

Özet

Purpose: Although the somatostatin analog octreotide is currently used in the treatment of chemotherapy-induced diarrhea and secretory diarrhea associated with various disorders, its role in the management of radiation enteritis is not well defined. We performed a randomized study that compared octreotide acetate with diphenoxylate hydrochloride plus atropine sulfate, the drug commonly used as therapy for acute radiation-induced diarrhea (ARID).