Central nervous system involvement in autoimmune polyglandular syndrome


Boz C. , Velioglu S. , Altunayoglu V. , Ozmenoglu M. , Erem C.

CLINICAL NEUROLOGY AND NEUROSURGERY, vol.105, no.2, pp.102-104, 2003 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 105 Issue: 2
  • Publication Date: 2003
  • Doi Number: 10.1016/s0303-8467(02)00125-7
  • Title of Journal : CLINICAL NEUROLOGY AND NEUROSURGERY
  • Page Numbers: pp.102-104

Abstract

We present a 33 year-old man, admitted because of transient deterioration of visual acuity. Magnetic resonance imaging showed diffuse central nervous system (CNS) demyelination, which largely resolved spontaneously within 4 months. The patient fulfilled the diagnostic criteria of APS type III, having autoimmune thyroiditis and alopecia universalis. In this patient, autoimmune activation against CNS antigens is thought to be the cause of reversible CNS demyelination. (C) 2002 Elsevier Science B.V. All rights reserved.