Improving a cortical pyramidal neuron model's classification performance on a real-world ecg dataset by extending inputs

Kayikcioglu Bozkir I., Özcan Z., Kose C., Kayikcioglu T., Cetin A. E.

JOURNAL OF COMPUTATIONAL NEUROSCIENCE, vol.51, no.3, pp.329-341, 2022 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 51 Issue: 3
  • Publication Date: 2022
  • Doi Number: 10.1007/s10827-023-00851-1
  • Journal Name: JOURNAL OF COMPUTATIONAL NEUROSCIENCE
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, BIOSIS, Biotechnology Research Abstracts, CAB Abstracts, EMBASE, INSPEC, MEDLINE, zbMATH
  • Page Numbers: pp.329-341
  • Keywords: ECG Data, Pyramidal Neurons, Machine Learning, Synaptic Inputs, Neural Dynamics, Biological Neural Networks, DENDRITIC INTEGRATION, COMPUTATION, PLASTICITY, IMPACT
  • Karadeniz Technical University Affiliated: Yes

Abstract

Pyramidal neurons display a variety of active conductivities and complex morphologies that support nonlinear dendritic computation. Given growing interest in understanding the ability of pyramidal neurons to classify real-world data, in our study we applied both a detailed pyramidal neuron model and the perceptron learning algorithm to classify real-world ECG data. We used Gray coding to generate spike patterns from ECG signals as well as investigated the classification performance of the pyramidal neuron's subcellular regions. Compared with the equivalent single-layer perceptron, the pyramidal neuron performed poorly due to a weight constraint. A proposed mirroring approach for inputs, however, significantly boosted the classification performance of the neuron. We thus conclude that pyramidal neurons can classify real-world data and that the mirroring approach affects performance in a way similar to non-constrained learning.