Carbonic Anhydrase Inhibition Potential and Some Bioactivities of the Peripherally Tetrasubstituted Cobalt(II), Titanium(IV), Manganese(III) Phthalocyanines


Karacelik A. A. , KÜÇÜK M. , Efe D., Cakir V., BIYIKLIOĞLU Z.

LETTERS IN DRUG DESIGN & DISCOVERY, vol.18, no.4, pp.365-371, 2021 (Journal Indexed in SCI) identifier identifier

  • Publication Type: Article / Article
  • Volume: 18 Issue: 4
  • Publication Date: 2021
  • Doi Number: 10.2174/1570180817999201009162347
  • Title of Journal : LETTERS IN DRUG DESIGN & DISCOVERY
  • Page Numbers: pp.365-371
  • Keywords: Metallophthalocyanines, carbonic anhydrase inhibition, antibacterial, antioxidant, biological activity, enzyme, PHOTOCHEMICAL PROPERTIES, THERAPEUTIC APPLICATIONS, ANTIBACTERIAL ACTIVITY, ANTIOXIDANT PROPERTIES, AGGREGATION BEHAVIOR, ENZYME-INHIBITION, METAL-FREE, DNA, DERIVATIVES, BINDING

Abstract

Background: Peripherally tetrasubstituted cobalt(II), titanium(IV), manganese(III) phthalocyanines carrying redox-active metal centers were previously synthesized. Metallophthalocyanines (MPcs) exhibited the potential to use in medicinal applications due to biological activities, such as antibacterial, antioxidant and enzyme inhibition.