The Kurtzke EDSS rank stability increases 4 years after the onset of multiple sclerosis: results from the MSBase Registry


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Hughes S., Spelman T., Trojano M., Lugaresi A., Izquierdo G., Grand'Maison F., ...Daha Fazla

JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, cilt.83, sa.3, ss.305-310, 2012 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 83 Konu: 3
  • Basım Tarihi: 2012
  • Doi Numarası: 10.1136/jnnp-2011-301051
  • Dergi Adı: JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY
  • Sayfa Sayıları: ss.305-310

Özet

Background The Expanded Disability Status Scale (EDSS) is widely used to rate multiple sclerosis (MS) disability, but lack of disease duration information limits utility in assessing severity. EDSS ranking at specific disease durations was used to devise the MS Severity Score, which is gaining popularity for predicting outcomes. As this requires validation in longitudinal cohorts, we aimed to assess the utility of EDSS ranking as a predictor of 5-year outcome in the MSBase Registry.