The Kurtzke EDSS rank stability increases 4 years after the onset of multiple sclerosis: results from the MSBase Registry

Hughes, Stella; Spelman, Timothy; Trojano, Maria; Lugaresi, Alessandra; Izquierdo, Guillermo; Grand'Maison, Francois; Duquette, Pierre; Girard, Marc; Grammond, Pierre; Oreja-Guevara, Celia; Hupperts, Raymond; BOZ, CAVİT; Bergamaschi, Roberto; Giuliani, Giorgio; Rio, Maria; Lechner-Scott, Jeannette; van Pesch, Vincent; Iuliano, Gerardo; Fiol, Marcela; Verheul, Freek; Barnett, Michael; Slee, Mark; Herbert, Joseph; Kister, Ilya; Vella, Norbert; Moore, Fraser; Petkovska-Boskova, Tatjana; Shaygannejad, Vahid; Jokubaitis, Vilija; McDonnell, Gavin; Hawkins, Stanley; Kee, Frank; Gray, Orla; Butzkueven, Helmut

doi:10.1136/jnnp-2011-301051

The Kurtzke EDSS rank stability increases 4 years after the onset of multiple sclerosis: results from the MSBase Registry

Hughes S., Spelman T., Trojano M., Lugaresi A., Izquierdo G., Grand'Maison F., ...Daha Fazla

JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, cilt.83, sa.3, ss.305-310, 2012 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 83 Sayı: 3
Basım Tarihi: 2012
Doi Numarası: 10.1136/jnnp-2011-301051
Dergi Adı: JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.305-310
Açık Arşiv Koleksiyonu: AVESİS Açık Erişim Koleksiyonu
Karadeniz Teknik Üniversitesi Adresli: Evet

Özet

Background The Expanded Disability Status Scale (EDSS) is widely used to rate multiple sclerosis (MS) disability, but lack of disease duration information limits utility in assessing severity. EDSS ranking at specific disease durations was used to devise the MS Severity Score, which is gaining popularity for predicting outcomes. As this requires validation in longitudinal cohorts, we aimed to assess the utility of EDSS ranking as a predictor of 5-year outcome in the MSBase Registry.