GGF2 Is Neuroprotective in a Rat Model of Cavernous Nerve Injury-Induced Erectile Dysfunction

Burnett A. L. , Sezen S. F. , Hoke A., CAGGIANO A. O. , IACI J., Lagoda G., ...Daha Fazla

JOURNAL OF SEXUAL MEDICINE, cilt.12, ss.897-905, 2015 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 12 Konu: 4
  • Basım Tarihi: 2015
  • Doi Numarası: 10.1111/jsm.12834
  • Dergi Adı: JOURNAL OF SEXUAL MEDICINE
  • Sayfa Sayıları: ss.897-905

Özet

IntroductionErectile dysfunction is a major complication of radical prostatectomy, commonly associated with penile neuropathy. In animal models of peripheral nerve injury, glial growth factor-2 (GGF2), a member of the neuregulin family of growth factors, has neuroprotective and neurorestorative properties, but this potential has not been established after cavernous nerve (CN) injury.