Comparison of Carotis İntima Media Thicknesses İn Gestational Weeks 24-26 and 36-38 İn Pregnant Women With Gestational Diabetes


KAĞITCI M., Balık G., ŞENTÜRK Ş., Tekin Y. B., Ural Ü. M., Şahin F. K., ...Daha Fazla

Eastern Journal of Medicine, cilt.28, sa.4, ss.618-623, 2023 (Scopus) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 28 Sayı: 4
  • Basım Tarihi: 2023
  • Doi Numarası: 10.5505/ejm.2023.57778
  • Dergi Adı: Eastern Journal of Medicine
  • Derginin Tarandığı İndeksler: Scopus, Academic Search Premier, CAB Abstracts, CINAHL, EMBASE, Veterinary Science Database, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.618-623
  • Anahtar Kelimeler: Atherosclerosis, Carotid intima media thickness, diabetes mellitus, gestational diabetes mellitus
  • Karadeniz Teknik Üniversitesi Adresli: Evet

Özet

The aim of this study is to investigate the differences between carotid intima media thickness (CIMT) of patients with gestational diabetes mellitus (GDM) and healthy pregnant women. METHODS: In this prospective study, 30 patients diagnosed with GDM and 30 healthy pregnant women were included. Serum HDL, LDL, TG, HbA1C and CRP levels, body mass indexes (BMI), and CIMT were measured for all participants included in the study. Measurements were repeated at 36-38 weeks of gestation. The difference between the second and third trimester measurements of both groups was compared. Second trimester CIMT measurements of GDM and healthy pregnant women were 5.483 ± 0.825 mm and 4.866 ± 0.642 mm, respectively, and the difference between the measurements of the two groups was statistically significant. Third trimester CIMT measurements of GDM and healthy pregnant women were 5.516±0.748 mm and 4.983 ±0.724 mm, respectively, and the difference between the measurements of the two groups was statistically significant (p=0.016). The difference between the second and third trimester CIMT measurements of the patients in the GDM group was not statistically significant (p=0.326). The difference between the second and third trimester CIMT measurements of the patients in the control group was not statistically significant (p=0.09). GDM patients are at risk for atherosclerosis. In treated GDM patients, the increase in CIMT can be prevented. These findings may indicate that with early diagnosis and treatment of GDM, our patients can be protected from the atosclerotic consequences of hyperglycemia.