4-(4-(( 5-Amino-1,3,4-thiadiazol-2-yl)methoxy) phenyl)-1-(( 5-amino-1,3,4-thiadiazol-2-yl)methyl)-3-benzyl-1H-1,2,4-triazol-5( H)-one: Synthesis, Characterization and Computational Studies

UNLUER, DİLEK; ÜNVER, YASEMİN; DUGDU, Esra; AKCAY, Hakki; SANCAK, KEMAL

doi:10.2174/1570178613666160930121719

4-(4-(( 5-Amino-1,3,4-thiadiazol-2-yl)methoxy) phenyl)-1-(( 5-amino-1,3,4-thiadiazol-2-yl)methyl)-3-benzyl-1H-1,2,4-triazol-5( H)-one: Synthesis, Characterization and Computational Studies

Atıf İçin Kopyala

UNLUER D., ÜNVER Y., DUGDU E., AKCAY H. T., SANCAK K.

LETTERS IN ORGANIC CHEMISTRY, cilt.13, sa.8, ss.604-617, 2016 (SCI-Expanded)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 13 Sayı: 8
Basım Tarihi: 2016
Doi Numarası: 10.2174/1570178613666160930121719
Dergi Adı: LETTERS IN ORGANIC CHEMISTRY
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.604-617
Karadeniz Teknik Üniversitesi Adresli: Evet

Özet

Background: 1,2,4-triazole and its derivatives are known to have various biological activities such as antifungal, antiviral, antidepressant, antitumor, anti-inflammatory, antitubercular, antimigrain and anti-cancer. Computational chemistry plays an important role in determining structural and chemical properties of chemical compounds. There are many studies on computational studies of triazole derivatives. The aim of this study is to prepare new triazole derivative having potent of bio-active material and to investigate the computational properties.