Comparison of levels of inflammatory markers and hemostatic factors in the patients with and without peripheral arterial disease


UNLU Y., Karapolat S., KARACA Y., KIZILTUNC A.

THROMBOSIS RESEARCH, vol.117, no.4, pp.357-364, 2006 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 117 Issue: 4
  • Publication Date: 2006
  • Doi Number: 10.1016/j.thromres.2005.03.019
  • Journal Name: THROMBOSIS RESEARCH
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.357-364
  • Karadeniz Technical University Affiliated: No

Abstract

Introduction: Peripheral arterial disease is one aspect of atherosclerosis, a disease associated with both inflammation and hypercoagulability. Many recent studies have focused on the diversity of mechanisms by which inflammation can promote blood clotting. However, the relationship between plasma concentrations of inflammatory and hemostatic markers and the severity of atherosclerosis is not yet well studied. We want to determine the relations among selected D-dimer, C-reactive protein, fibrinogen, prothrombin time and serum amyloid A, and the ankle brachial index in patients with and without peripheral arterial disease.