Akademik Veri Yönetim Sistemi
Turkish Journal of Analytical Chemistry, cilt.3, sa.1, ss.27-32, 2021 (Hakemli Dergi)
The acidic properties of ten 3-alkyl(aryl)-4-[3-hydroxy-4-methoxy benzylidenamino]-4,5-dihydro-1H-1,2,4-triazol-5-one derivatives were
investigated. Amphiprotic solvents used in this study were isopropyl alcohol and tert‐butanol. Acetone and N,N‐ dimethylformamide (DMF)
were preferred as a dipolar aprotic solvent. Compounds were titrated with tetrabutylammonium hydroxide (TBAH) in isopropyl alcohol and
titrimetric analyses were used potentiometric method determining the end-points, half-neutralization method determining acidity. Typical Sshaped titration graphs excepted were determined. The acidity strengths of 4,5-dihydro-1H-1,2,4-triazol-5-one derivatives in amphiprotic and
dipolar aprotic solvents were calculated using tables and graphs. The pKa values obtained in the solvents were found to be differentiated. The
effects of solvent, molecular structure, autoprotolysis constant dielectric constant, and leveling‐differentiation effects of the solvents upon acidity
strength of the compounds were discussed.