Dipyridamole reduces penile apoptosis in a rat model of post-prostatectomy erectile dysfunction


KUTLU Ö., KARAGÜZEL E. , Okatan A. E. , MENTEŞE A. , YULUĞ E. , KAZAZ İ. O. , ...More

INTERNATIONAL BRAZ J UROL, vol.43, no.5, pp.966-973, 2017 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 43 Issue: 5
  • Publication Date: 2017
  • Doi Number: 10.1590/s1677-5538.ibju.2017.0023
  • Title of Journal : INTERNATIONAL BRAZ J UROL
  • Page Numbers: pp.966-973
  • Keywords: Erectile Dysfunction, Dipyridamole, Penis, CAVERNOUS NERVE INJURY, NITRIC-OXIDE SYNTHASE, CORPORAL SMOOTH-MUSCLE, CORPUS CAVERNOSUM, RADICAL PROSTATECTOMY, ADENOSINE RECEPTORS, POSTRADICAL PROSTATECTOMY, PURINERGIC RESPONSES, CELLS, FIBROSIS

Abstract

Purpose: Despite the nerve-sparing technique, many patients suffer from erectile dysfunction after radical prostatectomy (RP) due to cavernous nerve injury. The aim of this study was to evaluate dipyridamole as a potential treatment agent of post-radical prostatectomy erectile dysfunction.