Dipyridamole reduces penile apoptosis in a rat model of post-prostatectomy erectile dysfunction

KUTLU Ö., KARAGÜZEL E., Okatan A. E., MENTEŞE A., YULUĞ E., KAZAZ İ. O., ...More

INTERNATIONAL BRAZ J UROL, vol.43, no.5, pp.966-973, 2017 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 43 Issue: 5
  • Publication Date: 2017
  • Doi Number: 10.1590/s1677-5538.ibju.2017.0023
  • Journal Name: INTERNATIONAL BRAZ J UROL
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.966-973
  • Keywords: Erectile Dysfunction, Dipyridamole, Penis, CAVERNOUS NERVE INJURY, NITRIC-OXIDE SYNTHASE, CORPORAL SMOOTH-MUSCLE, CORPUS CAVERNOSUM, RADICAL PROSTATECTOMY, ADENOSINE RECEPTORS, POSTRADICAL PROSTATECTOMY, PURINERGIC RESPONSES, CELLS, FIBROSIS
  • Karadeniz Technical University Affiliated: Yes

Abstract

Purpose: Despite the nerve-sparing technique, many patients suffer from erectile dysfunction after radical prostatectomy (RP) due to cavernous nerve injury. The aim of this study was to evaluate dipyridamole as a potential treatment agent of post-radical prostatectomy erectile dysfunction.