Infantile tremor syndrome secondary to peroral vitamin B12 replacement therapy: a report of two cases with myoclonus

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Dilber B., REİS G. P.

TURKISH JOURNAL OF PEDIATRICS, vol.63, no.3, pp.510-515, 2021 (SCI-Expanded) identifier identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 63 Issue: 3
  • Publication Date: 2021
  • Doi Number: 10.24953/turkjped.2021.03.020
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, CAB Abstracts, EMBASE, MEDLINE, Veterinary Science Database, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.510-515
  • Keywords: infantile tremor syndrome, myocolonic movement disorders, cerebral atrophy, peroral vitamin B12 therapy, RESONANCE-IMAGING FINDINGS, INVOLUNTARY MOVEMENTS, DEFICIENCY, CONSEQUENCES, DYSTONIA
  • Karadeniz Technical University Affiliated: Yes


Background. Abnormal movements such as tremors and myoclonus may be observed during both treatment and deficiency of vitamin B12, particularly in infants. Infantile tremor syndrome (ITS) is defined by the tetrad of pallor, developmental delay/regression, skin pigmentation, and brown scanty scalp hair.