Does pain sensitivity increase during ictal period? Evidence from absence epileptic WAG/Rij rats


VELİOĞLU S., GEDİKLİ Ö., Yildirim M., AYAR A.

EPILEPSY & BEHAVIOR, cilt.87, ss.14-17, 2018 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 87
  • Basım Tarihi: 2018
  • Doi Numarası: 10.1016/j.yebeh.2018.08.001
  • Dergi Adı: EPILEPSY & BEHAVIOR
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.14-17
  • Anahtar Kelimeler: Epilepsy, Pain, Genetic absence epilepsy, WAG/Rij rats, Pain threshold, Ictal nociception, SEROTONERGIC RECEPTORS, SEIZURES, ANALGESIA, CONSCIOUSNESS, MODELS, STRAIN
  • Karadeniz Teknik Üniversitesi Adresli: Evet

Özet

Objective: The hyperexdtable brain provides a common ground for comorbidity of pain syndromes and epilepsy. There are controversial reports about pain sensitivity during the ictal period. We analyzed the pain sensitivity during the ictal period in the genetic absence epilepsy animal model, Wistar Albino Glaxo/Rijswijk (WAG/Rij) rats.