Does pain sensitivity increase during ictal period? Evidence from absence epileptic WAG/Rij rats


VELİOĞLU S. , GEDİKLİ Ö. , Yildirim M., AYAR A.

EPILEPSY & BEHAVIOR, vol.87, pp.14-17, 2018 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 87
  • Publication Date: 2018
  • Doi Number: 10.1016/j.yebeh.2018.08.001
  • Title of Journal : EPILEPSY & BEHAVIOR
  • Page Numbers: pp.14-17
  • Keywords: Epilepsy, Pain, Genetic absence epilepsy, WAG/Rij rats, Pain threshold, Ictal nociception, SEROTONERGIC RECEPTORS, SEIZURES, ANALGESIA, CONSCIOUSNESS, MODELS, STRAIN

Abstract

Objective: The hyperexdtable brain provides a common ground for comorbidity of pain syndromes and epilepsy. There are controversial reports about pain sensitivity during the ictal period. We analyzed the pain sensitivity during the ictal period in the genetic absence epilepsy animal model, Wistar Albino Glaxo/Rijswijk (WAG/Rij) rats.