Migraine-related seizures in an epileptic population


Velioglu S. , Ozmenoglu M.

CEPHALALGIA, cilt.19, ss.797-801, 1999 (SCI İndekslerine Giren Dergi) identifier identifier identifier

Özet

A relationship between epilepsy and migraine has long been postulated, but the nature of this interaction is still debated. We studied adult patients with epilepsy and investigated the relationship between migraine and epilepsy. Fourteen percent (n=412) of adult patients with seizures were identified with a diagnosis of migraine. We also found a direct relationship between migraine and epilepsy (a migraine-induced epilepsy) in 1.7% (seven patients) of the patients with seizures. Patients were at increased risk for both conditions if they had migraine with aura and catamenial epilepsy. The seizure began during or shortly after the migraine aura in all of the cases and preceded the headache. Three of four patients who were refractory to management with antiepileptic drugs using either mono or combination therapy improved seizure control with combination antimigraine and antiepileptic drugs.

A relationship  between epilepsy  and  migraine has long been postulated, but the nature of this interaction  is
still debated.  We studied  adult  patients with  epilepsy and  investigated the  relationship between migraine
and  epilepsy. Fourteen percent  (n=412)  of adult patients with seizures were  identified  with  a diagnosis of
migraine. We also found a direct relationship  between migraine and epilepsy (a migraine-induced epilepsy)
in  1.7% (seven patients) of the patients with seizures. Patients were at increased risk for both  conditions if
they  had  migraine  with  aura  and  catamenial  epilepsy.  The  seizure  began  during  or  shortly  after  the
migraine aura  in  all of the cases and preceded  the headache. Three of four  patients who  were refractory to
management with antiepileptic  drugs  using either mono  or  combination therapy  improved  seizure control
with  combination  antimigraine and  antiepileptic drugs.