Comparative Volatile Composition, Phenolic Contents, and Antimicrobial Activities of the Essential Oils and Solvent Extracts of Orthomnion Rostratum and Orthomnion Medium
BRAZILIAN JOURNAL OF PHARMACEUTICAL SCIENCES, sa.e24921, ss.1, 2026 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Basım Tarihi: 2026
- Doi Numarası: 10.1590/s2175-97902026e24921
- Dergi Adı: BRAZILIAN JOURNAL OF PHARMACEUTICAL SCIENCES
- Derginin Tarandığı İndeksler: Health Research Premium Collection (ProQuest), Scopus, Science Citation Index Expanded (SCI-EXPANDED), BIOSIS, EMBASE, Directory of Open Access Journals
- Sayfa Sayıları: ss.1
- Karadeniz Teknik Üniversitesi Adresli: Evet
Özet
The present study aimed to investigate the chemical composition of essential oils (EOs) and methanol extracts of Orthomnion rostratum and Orthomnion medium species. The EOs were obtained using hydrodistillation (HD) and microwave distillation (MWD) and analyzed by GC-FID-MS. Octanal (24.12%, HD; 20.22%, MWD), pentanal (31.45%, HD), and n-pentanol (25.50%, MWD) were found to be significant compounds, respectively. Analysis of the phenolic constituents of the methanol extracts of O. rostratum and O. medium yielded apigenin glucoside derivatives as the major compounds, with concentrations of 1.355 and 0.382 mg/g, respectively. The antimicrobial activities of the EOs and solvent extracts (n-hexane, chloroform, methanol, and water) of both species were evaluated against nine microorganisms. EOs obtained using MWD from both species exhibited the strongest antimicrobial activity against Staphylococcus aureus (15.9 µg/mL and 15.0 µg/mL), Enterococcus faecalis (31.9 µg/mL and 30.0 µg/mL), Bacillus cereus (15.9 µg/mL and 15.0 µg/mL), respectively