THE EFFECTS OF FARNESYLTRANSFERASE INHIBITOR L-744,832 AND RADIOTHERAPY ON H-RAS+(SVR A221A) CELL LINE
NOBEL MEDICUS, vol.8, no.3, pp.76-80, 2012 (SCI-Expanded, Scopus)
- Publication Type: Article / Article
- Volume: 8 Issue: 3
- Publication Date: 2012
- Journal Name: NOBEL MEDICUS
- Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Page Numbers: pp.76-80
- Karadeniz Technical University Affiliated: Yes
Abstract
Objective: We planned to assess the effects of two doses farnesyltransferase enzyme inhibitor L-744,832, either alone or in combination with low, medium, and high dose radiation on cultured H-Ras positive cells (SVR A221a) regarding the cell count, DNA indices and apoptosis determined by flow-cytometric method.