THE EFFECTS OF FARNESYLTRANSFERASE INHIBITOR L-744,832 AND RADIOTHERAPY ON H-RAS+(SVR A221A) CELL LINE


ÖZDEMİR F., Kavgaci H., OVALI E., YILMAZ M., YILDIZ B., AYDIN F.

NOBEL MEDICUS, cilt.8, sa.3, ss.76-80, 2012 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 8 Sayı: 3
  • Basım Tarihi: 2012
  • Dergi Adı: NOBEL MEDICUS
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.76-80
  • Karadeniz Teknik Üniversitesi Adresli: Evet

Özet

Objective: We planned to assess the effects of two doses farnesyltransferase enzyme inhibitor L-744,832, either alone or in combination with low, medium, and high dose radiation on cultured H-Ras positive cells (SVR A221a) regarding the cell count, DNA indices and apoptosis determined by flow-cytometric method.