THE EFFECTS OF FARNESYLTRANSFERASE INHIBITOR L-744,832 AND RADIOTHERAPY ON H-RAS+(SVR A221A) CELL LINE


ÖZDEMİR F. , Kavgaci H. , OVALI E., YILMAZ M. , YILDIZ B., AYDIN F.

NOBEL MEDICUS, vol.8, no.3, pp.76-80, 2012 (Journal Indexed in SCI) identifier identifier

  • Publication Type: Article / Article
  • Volume: 8 Issue: 3
  • Publication Date: 2012
  • Title of Journal : NOBEL MEDICUS
  • Page Numbers: pp.76-80

Abstract

Objective: We planned to assess the effects of two doses farnesyltransferase enzyme inhibitor L-744,832, either alone or in combination with low, medium, and high dose radiation on cultured H-Ras positive cells (SVR A221a) regarding the cell count, DNA indices and apoptosis determined by flow-cytometric method.