In Vivo Effects of Naringenin and Lead on Rat Erythrocyte Carbonic Anhydrase Enzyme

Kuzu M., Ozkaya A., Sahin Z., Dag U., Comakli V., Demirdag R.

TURKISH JOURNAL OF PHARMACEUTICAL SCIENCES, vol.14, no.1, pp.9-12, 2017 (ESCI) identifier identifier

  • Publication Type: Article / Article
  • Volume: 14 Issue: 1
  • Publication Date: 2017
  • Doi Number: 10.4274/tjps.13008
  • Journal Name: TURKISH JOURNAL OF PHARMACEUTICAL SCIENCES
  • Journal Indexes: Emerging Sources Citation Index (ESCI), Scopus, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.9-12
  • Keywords: Carbonic anhydrase, inhibition, lead, naringenin, GLUTATHIONE-S-TRANSFERASE, METAL-IONS, HEAVY-METALS, LIVER, PURIFICATION, GLUCOSE-6-PHOSPHATE-DEHYDROGENASE, INHIBITION, SYSTEM
  • Karadeniz Technical University Affiliated: No

Abstract

Objectives: Carbonic anhydrase (CA) enzyme catalyses the reversible reactions of CO2 with water and takes part in metabolically important events such as systemic acid-base regulation and respiration. In this study, in vivo effects of lead, which is a heavy metal and to which living beings are exposed by different ways, with naringenin, a flavanone, were investigated.