In Vivo Effects of Naringenin and Lead on Rat Erythrocyte Carbonic Anhydrase Enzyme

Kuzu M., Ozkaya A., Sahin Z., Dag U., Comakli V., Demirdag R.

TURKISH JOURNAL OF PHARMACEUTICAL SCIENCES, cilt.14, sa.1, ss.9-12, 2017 (ESCI) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 14 Sayı: 1
  • Basım Tarihi: 2017
  • Doi Numarası: 10.4274/tjps.13008
  • Dergi Adı: TURKISH JOURNAL OF PHARMACEUTICAL SCIENCES
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.9-12
  • Anahtar Kelimeler: Carbonic anhydrase, inhibition, lead, naringenin, GLUTATHIONE-S-TRANSFERASE, METAL-IONS, HEAVY-METALS, LIVER, PURIFICATION, GLUCOSE-6-PHOSPHATE-DEHYDROGENASE, INHIBITION, SYSTEM
  • Karadeniz Teknik Üniversitesi Adresli: Hayır

Özet

Objectives: Carbonic anhydrase (CA) enzyme catalyses the reversible reactions of CO2 with water and takes part in metabolically important events such as systemic acid-base regulation and respiration. In this study, in vivo effects of lead, which is a heavy metal and to which living beings are exposed by different ways, with naringenin, a flavanone, were investigated.