Akademik Veri Yönetim Sistemi
Turkiye Klinikleri Jinekoloji Obstetrik, cilt.22, sa.2, ss.90-94, 2012 (Scopus)
Objective: Drug use in pregancy is a major obstetric issue due to the potential teratogenic effects. There are restricted studies about drug use during the first trimester in our country. The aim of this investigation is to evaluate pregnancies which applied to two reference hospitals of west and northeast of Turkey for drug use retrospectively and to initiate further studies in this field. Material and Methods: This study was performed at Obstetrics and Gynecology and Pharmacology deaprtments of Celal Bayar University Hospital (CBU) in Manisa and Trabzon Technical University Hospital (KTU) in Trabzon. Pregnancies who applied between 2005-2010 at any week of gestation with a history of drug use were retrospectively evaluated. Results: A total of 811 records were analysed. The most frequent drug used in Manisa and Trabzon was antidepressants (19%, 38.3%) and antibiotics (17.8%, 32.9%). Antiepileptics ranked third at CBU (11.7%) and analgesics at KTU (23.3%). When the most freqently used drug groups were compared there was a significant difference. Pregnant women used drugs of Food and Drug Administration group C 58.1%, D 23.2%, B 14.2% and X 4.5% while in Trabzon there was a drug use of 82.7% low risk, 11.6% intermediate, 4.7% noncategorised and 0.9% high risk groups. Conclusion: There is a common belief that antidepressants and antibiotics are harmful for the fetus. Patients are more susceptible to consult a doctor when these two groups are consumed during pregnancy. It is important to raise awareness about planned pregnancies and educate women about medications during a possible pregnancy. Questioning about pregnancy before prescibing drugs will lower the risk of teratogenity. Copyright © 2012 by Türkiye Klinikleri.