This study examined the applicability of mastery learning model in music education in line with the implementation principals. Essentials of mastery learning model and implementation requirements were applied on the subject selected within the curriculum. In the study that was conducted with the 10th grade students of Anatolian Teachers' High School, "Major and Minor Scales" were selected as subject for students to study. The subjects were taught through mastery learning model and a higher level of learning was achieved in the experiment group as the study included two separate groups as the Experiment Group and the Control Group. The selected subject was taught through conventional learning methods in the control group. The study with the experiment group included activities such as pre-test, elimination of shortcomings, a hands-on study, feedback and post-test after the correction. Scores of students were comparatively assessed in the outcome of the study. The data obtained have suggested that the mastery learning practice is more successful than the classical learning practice.