Synthesis and Biological Activities of Some New 4,5-dihydro-1H-1,2,4-Triazol-5-ones

DEMİRBAŞ A., Johansson C. B. , Duman N., İKİZLER A. A.

Other, pp.117-121, 1996

  • Publication Type: Other Publication / Other
  • Publication Date: 1996
  • Page Numbers: pp.117-121


The reactions of 3-alkyl(aryl)-4-phenylamino-4,5-dihydro-1H-1,2,4-triazol-5-oneswith appropriate alkyl halides via sodio derivatives were studied and the corresponding 1-alkyl-3-alkyl(aryl)-4-phenylamino-4,5-dihydro-1H-1,2,4-traizol-5-ones were synthesized. Next, the new compounds were tested for their in vitro antimicrobial activities.