Acute liver failure associated with metabolic diseases: A 10-year single-center experience

GÜVEN B., Sag E., KARAGÜZEL G., ÇAKIR M.

PEDIATRICS INTERNATIONAL, cilt.62, sa.5, ss.609-614, 2020 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 62 Sayı: 5
  • Basım Tarihi: 2020
  • Doi Numarası: 10.1111/ped.14230
  • Dergi Adı: PEDIATRICS INTERNATIONAL
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, Agricultural & Environmental Science Database, BIOSIS, CAB Abstracts, CINAHL, EMBASE, MEDLINE, Veterinary Science Database
  • Sayfa Sayıları: ss.609-614
  • Anahtar Kelimeler: acute liver failure, metabolic disease, pediatric, CHILDREN, DISORDERS, TRANSPLANTATION, DEFICIENCY, OUTCOMES, INFANTS
  • Karadeniz Teknik Üniversitesi Adresli: Evet

Özet

Background Acute liver failure (ALF) is a rare multisystemic disease occurring in individuals with no history of liver disease, characterized by coagulopathy and / or hepatic encephalopathy secondary to acute liver injury. It is mostly caused by viral infections, drug intoxication, and metabolic diseases (MD), and can also have an indeterminate etiology. In this study, we aimed to evaluate the demographic and clinical characteristics and clinical outcomes of the patients that presented to our clinic with MD-associated ALF.