The Role of Nitric Oxide in Doxorubicin-Induced Cardiotoxicity: Experimental Study

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Bahadır A., Kurucu N., Kadioglu M., Yenilmez E.

TURKISH JOURNAL OF HEMATOLOGY, vol.31, no.1, pp.68-74, 2014 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 31 Issue: 1
  • Publication Date: 2014
  • Doi Number: 10.4274/tjh.2013.0013
  • Journal Name: TURKISH JOURNAL OF HEMATOLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.68-74
  • Keywords: Doxorubicin, Nitric oxide, Nitric oxide synthase inhibitors, HEART-FAILURE, RAT-HEART, SYNTHASE, CARDIOMYOPATHY, DYSFUNCTION, ADRIAMYCIN, TOXICITY, SUPEROXIDE, ERDOSTEINE, PREVENTION
  • Karadeniz Technical University Affiliated: Yes

Abstract

Objective: We evaluated the myocardial damage in rats treated with doxorubicin (DOX) alone and in combination with nitric oxide synthase (NOS) inhibitors.