Ethyl pyruvate treatment ameliorates pancreatic damage: evidence from a rat model of acute necrotizing pancreatitis


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Türkyılmaz S. , Çekiç A. B. , Usta A. , Alhan E. , Kural B. , Ercin C., ...More

ARCHIVES OF MEDICAL SCIENCE, vol.15, no.1, pp.232-239, 2019 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 15 Issue: 1
  • Publication Date: 2019
  • Doi Number: 10.5114/aoms.2017.65231
  • Title of Journal : ARCHIVES OF MEDICAL SCIENCE
  • Page Numbers: pp.232-239

Abstract

Introduction: Ethyl pyruvate (EP), a natural flavoring and fragrance agent, has been shown to exert anti-inflammatory and antioxidant actions. We tested the potential beneficial effects of EP in a rat model of acute necrotizing pancreatitis (ANP), a serious condition with a significant inflammatory explosion and oxidative stress.