Ethyl pyruvate treatment ameliorates pancreatic damage: evidence from a rat model of acute necrotizing pancreatitis
ARCHIVES OF MEDICAL SCIENCE, cilt.15, sa.1, ss.232-239, 2019 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 15 Sayı: 1
- Basım Tarihi: 2019
- Doi Numarası: 10.5114/aoms.2017.65231
- Dergi Adı: ARCHIVES OF MEDICAL SCIENCE
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.232-239
- Anahtar Kelimeler: pancreatitis, rat, ethyl pyruvate, acute necrotizing pancreatitis, IMPROVES SURVIVAL, OXIDATIVE STRESS, FREE-RADICALS, LIVER-INJURY, ACCUMULATION, PATHOGENESIS, ISCHEMIA
- Açık Arşiv Koleksiyonu: AVESİS Açık Erişim Koleksiyonu
- Karadeniz Teknik Üniversitesi Adresli: Evet
Özet
Introduction: Ethyl pyruvate (EP), a natural flavoring and fragrance agent, has been shown to exert anti-inflammatory and antioxidant actions. We tested the potential beneficial effects of EP in a rat model of acute necrotizing pancreatitis (ANP), a serious condition with a significant inflammatory explosion and oxidative stress.