Ethyl pyruvate treatment ameliorates pancreatic damage: evidence from a rat model of acute necrotizing pancreatitis
ARCHIVES OF MEDICAL SCIENCE, vol.15, no.1, pp.232-239, 2019 (SCI-Expanded, Scopus)
- Publication Type: Article / Article
- Volume: 15 Issue: 1
- Publication Date: 2019
- Doi Number: 10.5114/aoms.2017.65231
- Journal Name: ARCHIVES OF MEDICAL SCIENCE
- Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Page Numbers: pp.232-239
- Keywords: pancreatitis, rat, ethyl pyruvate, acute necrotizing pancreatitis, IMPROVES SURVIVAL, OXIDATIVE STRESS, FREE-RADICALS, LIVER-INJURY, ACCUMULATION, PATHOGENESIS, ISCHEMIA
- Open Archive Collection: AVESIS Open Access Collection
- Karadeniz Technical University Affiliated: Yes
Abstract
Introduction: Ethyl pyruvate (EP), a natural flavoring and fragrance agent, has been shown to exert anti-inflammatory and antioxidant actions. We tested the potential beneficial effects of EP in a rat model of acute necrotizing pancreatitis (ANP), a serious condition with a significant inflammatory explosion and oxidative stress.