Effects of intraoperative blood loss during liver resection on patients’ outcome: a single- center experience.

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Bodur M. S., Tomas K., Topaloğlu S., Oğuz Ş., Küçükaslan H., Dohman D., ...Daha Fazla

Turkish journal of medical sciences, cilt.51, sa.3, ss.1388-1395, 2021 (SCI-Expanded) identifier identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 51 Sayı: 3
  • Basım Tarihi: 2021
  • Doi Numarası: 10.3906/sag-2008-78
  • Dergi Adı: Turkish journal of medical sciences
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, CAB Abstracts, EMBASE, MEDLINE, Veterinary Science Database, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.1388-1395
  • Anahtar Kelimeler: Liver surgery, operative bleeding, portal triad clamping, low central venous pressure, hemostasis, HEPATECTOMY, SURGERY
  • Karadeniz Teknik Üniversitesi Adresli: Evet

Özet

Background/aim: Operative bleeding is one of the major determinants of outcome in liver surgery. This study aimed to describe the impact of intraoperative blood loss on the postoperative course of liver resection (LR).   

Materials and methods: The data of 257 patients who were treated with LR between January 2007 and October 2018 were retrospectively analyzed. LRs were performed via intermittent portal triad clamping (PTC) under low central venous pressure.

Results: LRs were performed for 67.7% of patients with a malignant disease and 32.3% of patients with a benign disease. Major LR was performed in 89 patients (34.6%). The mean PTC period was 20.32 minutes (±13.7). The median intraoperative bleeding amount was 200 ml (5-3500 ml), the 30-day mortality rate was 4.3%, and the morbidity rate was 31.9%. The hospital stay (P=0.002), morbidity (P=0.009), and 30-day mortality (P=0.041) of patients with a bleeding amount of more than 500 ml significantly increased.

Conclusion: Surgeons should consider the adverse effects of intraoperative bleeding during liver resection on patients’ outcome. Favorable outcomes would be obtained with diligent postoperative care.