Effects of erythropoietin on spontaneous and oxytocin induced myometrial contractions in the nonpregnant rat


Tug N., Tasan H. A. , Sargin M. A. , Taymur B. D. , Ayar A. , Kilic E., ...More

EUROPEAN REVIEW FOR MEDICAL AND PHARMACOLOGICAL SCIENCES, vol.21, no.22, pp.5028-5033, 2017 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 21 Issue: 22
  • Publication Date: 2017
  • Doi Number: 10.26355/eurrev_201711_13814
  • Title of Journal : EUROPEAN REVIEW FOR MEDICAL AND PHARMACOLOGICAL SCIENCES
  • Page Numbers: pp.5028-5033

Abstract

OBJECTIVE: Erythropoietin (EPO) is a glycoprotein hormone that regulates erythropoiesis. EPO activity has also been detected in a variety of tissue including the nervous system, and female and male reproductive organs. It has been shown that EPO causes relaxation in vascular smooth muscle. In the present study, we have investigated effects of EPO on spontaneous and oxytocin-induced contractions of non-pregnant rat myometrium.