The Relationship between Metabolic Parameters, Cardiac Parameters and MIC-1/GDF15 in Obese Children

Yuca S. A., Cimbek E. A., Sen Y., Guevenc O., Vatansev H., Bugrul F., ...Daha Fazla

EXPERIMENTAL AND CLINICAL ENDOCRINOLOGY & DIABETES, cilt.125, sa.2, ss.86-90, 2017 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 125 Sayı: 2
  • Basım Tarihi: 2017
  • Doi Numarası: 10.1055/s-0042-114220
  • Dergi Adı: EXPERIMENTAL AND CLINICAL ENDOCRINOLOGY & DIABETES
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.86-90
  • Anahtar Kelimeler: obesity, MIC-1/GDF15, inflammation, cardiovascular risk management, MACROPHAGE INHIBITORY CYTOKINE-1, GROWTH-DIFFERENTIATION FACTOR-15, CHILDHOOD OBESITY, HEART, ANOREXIA, MARKER
  • Karadeniz Teknik Üniversitesi Adresli: Hayır

Özet

Objective: Childhood obesity which is a predictor of adulthood obesity is associated with type 2 diabetes, metabolic syndrome, dyslipidemia, coronary artery diseases and subclinical inflammation. Growth differentiation factor-15, also known as macrophage inhibitory cytokine-1 (MIC-1/GDF15) is a member of the transforming growth factor-super family and increases during inflammatory states. Adults with obesity have increased serum concentrations of MIC-1/GDF15.MIC-1/GDF15 is associated with cardio metabolic risk in adults.