Lipid peroxidation levels and total oxidant status in serum, saliva and gingival crevicular fluid in patients with chronic periodontitis


Akalin F. A. , Baltacioglu E. , Alver A. , Karabulut E.

JOURNAL OF CLINICAL PERIODONTOLOGY, vol.34, no.7, pp.558-565, 2007 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 34 Issue: 7
  • Publication Date: 2007
  • Doi Number: 10.1111/j.1600-051x.2007.01091.x
  • Title of Journal : JOURNAL OF CLINICAL PERIODONTOLOGY
  • Page Numbers: pp.558-565
  • Keywords: chronic periodontitis, gingival crevicular fluid, lipid peroxidation, malondialdehyde, oxidative stress, saliva, TOTAL ANTIOXIDANT CAPACITY, DISMUTASE ACTIVITY LEVELS, OXIDATIVE STRESS, OXYGEN RADICALS, DISEASE PROGRESSION, RISK-FACTOR, PROTECTION, INTERLEUKIN-1-BETA, MALONDIALDEHYDE, PATHOGENESIS

Abstract

Objectives: Increased levels of reactive oxygen species lead to oxidative stress. Recent data suggest increased lipid peroxidation (LPO) levels and oxidative stress in periodontitis. Malondialdehyde (MDA), a significant LPO product, increases in oxidative stress. In this study, MDA levels and total oxidant status (TOS) in serum, saliva and gingival crevicular fluid (GCF) were investigated in patients with chronic periodontitis (CP).