Lipid peroxidation levels and total oxidant status in serum, saliva and gingival crevicular fluid in patients with chronic periodontitis

Akalin F. A., Baltacioglu E., Alver A., Karabulut E.

JOURNAL OF CLINICAL PERIODONTOLOGY, cilt.34, sa.7, ss.558-565, 2007 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 34 Sayı: 7
  • Basım Tarihi: 2007
  • Doi Numarası: 10.1111/j.1600-051x.2007.01091.x
  • Dergi Adı: JOURNAL OF CLINICAL PERIODONTOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.558-565
  • Anahtar Kelimeler: chronic periodontitis, gingival crevicular fluid, lipid peroxidation, malondialdehyde, oxidative stress, saliva, TOTAL ANTIOXIDANT CAPACITY, DISMUTASE ACTIVITY LEVELS, OXIDATIVE STRESS, OXYGEN RADICALS, DISEASE PROGRESSION, RISK-FACTOR, PROTECTION, INTERLEUKIN-1-BETA, MALONDIALDEHYDE, PATHOGENESIS
  • Karadeniz Teknik Üniversitesi Adresli: Evet

Özet

Objectives: Increased levels of reactive oxygen species lead to oxidative stress. Recent data suggest increased lipid peroxidation (LPO) levels and oxidative stress in periodontitis. Malondialdehyde (MDA), a significant LPO product, increases in oxidative stress. In this study, MDA levels and total oxidant status (TOS) in serum, saliva and gingival crevicular fluid (GCF) were investigated in patients with chronic periodontitis (CP).