Diagnostic Significance of Ischemia-Modified Albumin, S100b, and Neuron-Specific Enolase in Acute Ischemic Stroke

Cakmak V. A., GÜNDÜZ A., KARACA Y., ALİOĞLU Z., MENTEŞE A., TOPBAŞ M.

EURASIAN JOURNAL OF EMERGENCY MEDICINE, vol.13, no.3, pp.112-117, 2014 (ESCI) identifier

  • Publication Type: Article / Article
  • Volume: 13 Issue: 3
  • Publication Date: 2014
  • Doi Number: 10.5152/jaem.2014.37980
  • Journal Name: EURASIAN JOURNAL OF EMERGENCY MEDICINE
  • Journal Indexes: Emerging Sources Citation Index (ESCI), TR DİZİN (ULAKBİM)
  • Page Numbers: pp.112-117
  • Keywords: Ischemic stroke, ischemic modified albumin, S100 calcium-binding protein beta subunit, neuron-specific enolase, biomarker
  • Karadeniz Technical University Affiliated: Yes

Abstract

Objective: Use of biochemical markers of cerebral ischemia is a newly favored approach for early diagnosis of ischemic stroke. Our aim was to establish the sensitivity and specificity of ischemia-modified albumin (IMA) in acute ischemic stroke and to compare it with S100b and neuron-specific enolase (NSE). We also intended to investigate the usefulness of a panel composed of these three biomarkers in acute ischemic stroke.