Cataractous changes in rat lens following cigarette smoke exposure is prevented by parenteral deferoxamine therapy

Avunduk, AM; Yardimci, S; Avunduk, MC; Kurnaz, L

doi:10.1001/archopht.117.10.1368

Cataractous changes in rat lens following cigarette smoke exposure is prevented by parenteral deferoxamine therapy

Avunduk A., Yardimci S., Avunduk M., Kurnaz L.

ARCHIVES OF OPHTHALMOLOGY, cilt.117, sa.10, ss.1368-1372, 1999 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 117 Sayı: 10
Basım Tarihi: 1999
Doi Numarası: 10.1001/archopht.117.10.1368
Dergi Adı: ARCHIVES OF OPHTHALMOLOGY
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.1368-1372
Açık Arşiv Koleksiyonu: AVESİS Açık Erişim Koleksiyonu
Karadeniz Teknik Üniversitesi Adresli: Hayır

Özet

Objectives: To test whether iron accumulation in the lens following cigarette smoke exposure is the principal mechanism in smoke-related cataractogenesis and to assess the possible protective effect of deferoxamine mesylate treatment against lenticular degeneration with in vivo exposure to cigarette smoke.