Cataractous changes in rat lens following cigarette smoke exposure is prevented by parenteral deferoxamine therapy

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Avunduk A., Yardimci S., Avunduk M., Kurnaz L.

ARCHIVES OF OPHTHALMOLOGY, vol.117, no.10, pp.1368-1372, 1999 (SCI-Expanded, Scopus)

• Publication Type: Article / Article
• Volume: 117 Issue: 10
• Publication Date: 1999
• Doi Number: 10.1001/archopht.117.10.1368
• Journal Name: ARCHIVES OF OPHTHALMOLOGY
• Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
• Page Numbers: pp.1368-1372
• Open Archive Collection: AVESIS Open Access Collection
• Karadeniz Technical University Affiliated: No

Abstract

Objectives: To test whether iron accumulation in the lens following cigarette smoke exposure is the principal mechanism in smoke-related cataractogenesis and to assess the possible protective effect of deferoxamine mesylate treatment against lenticular degeneration with in vivo exposure to cigarette smoke.